Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

Diethyl 3-hydroxyglutarate

Related Products

Hot Products

Name

Diethyl 3-hydroxyglutarate

EINECS 250-992-6
CAS No. 32328-03-3 Density 1.122 g/cm3
PSA 72.83000 LogP 0.25370
Solubility N/A Melting Point 48oC
Formula C9H16O5 Boiling Point 256.5 °C at 760 mmHg
Molecular Weight 204.223 Flash Point 110.7 °C
Transport Information N/A Appearance Light yellow to colorless liquid
Safety 23-24/25 Risk Codes N/A
Molecular Structure Molecular Structure of 32328-03-3 (Diethyl 3-hydroxyglutarate) Hazard Symbols N/A
Synonyms

Glutaricacid, 3-hydroxy-, diethyl ester (6CI,7CI);Pentanedioic acid, 3-hydroxy-,diethyl ester (9CI);3-Hydroxyglutaric acid diethyl ester;Diethyl 3-hydroxypentanedioate;NSC 62681;

Article Data 16

Diethyl 3-hydroxyglutarate Synthetic route

105-50-0

diethyl 1,3-acetonedicarboxylate

32328-03-3

diethyl 3-hydroxyglutarate

Conditions
ConditionsYield
With sodium tetrahydroborate; ethanol at 0℃; for 0.05h;95%
With sodium amalgam
With 1,4-dioxane; nickel Hydrogenation;
638-18-6

diethyl 3-hydroxypentanedioate

64-17-5

ethanol

32328-03-3

diethyl 3-hydroxyglutarate

Conditions
ConditionsYield
With sulfuric acid
With sulfuric acid
64-17-5

ethanol

13880-89-2

3-hydroxyglutaronitrile

32328-03-3

diethyl 3-hydroxyglutarate

Conditions
ConditionsYield
With sulfuric acid at 90 - 100℃;
With hydrogenchloride In diethyl ether
13880-89-2

3-hydroxyglutaronitrile

32328-03-3

diethyl 3-hydroxyglutarate

106-95-6

allyl bromide

105-50-0

diethyl 1,3-acetonedicarboxylate

32328-03-3

diethyl 3-hydroxyglutarate

Conditions
ConditionsYield
With sodium ethanolate 1.) EtOH, r.t., overnight, 2.) baker's yeast, H2O, 30 deg C, 72 h; Yield given. Multistep reaction;
105-50-0

diethyl 1,3-acetonedicarboxylate

Raney nickel

Raney nickel

32328-03-3

diethyl 3-hydroxyglutarate

Conditions
ConditionsYield
Hydrogenation;
64-17-5

ethanol

121-44-8

triethylamine

105-50-0

diethyl 1,3-acetonedicarboxylate

Raney nickel

Raney nickel

A

32328-03-3

diethyl 3-hydroxyglutarate

B

4328-94-3

pentane-1,3,5-triol

Conditions
ConditionsYield
at 125℃; under 250073 Torr; Hydrogenation;
542-05-2

acetonedicarboxylic acid

32328-03-3

diethyl 3-hydroxyglutarate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
2: sodium amalgam
View Scheme
1830-54-2

3-oxopentanedioic acid dimethyl ester

32328-03-3

diethyl 3-hydroxyglutarate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: NaBH4 / methanol
2: KOH / methanol
3: H2SO4
View Scheme
7250-55-7

dimethyl 3-hydroxypentanedioate

32328-03-3

diethyl 3-hydroxyglutarate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: KOH / methanol
2: H2SO4
View Scheme

Diethyl 3-hydroxyglutarate Specification

The Pentanedioic acid,3-hydroxy-, 1,5-diethyl ester, with CAS registry number 32328-03-3, belongs to the following product categories: (1)C8 to C9; (2)Carbonyl Compounds; (3)Esters. It has the systematic name of diethyl 3-hydroxypentanedioate. What's more, its EINECS is 250-992-6.

Physical properties of Pentanedioic acid,3-hydroxy-, 1,5-diethyl ester: (1)ACD/LogP: 0.29; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 0.29; (4)ACD/LogD (pH 7.4): 0.29; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 34.33; (8)ACD/KOC (pH 7.4): 34.33; (9)#H bond acceptors: 5; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 9; (12)Polar Surface Area: 61.83 Å2; (13)Index of Refraction: 1.448; (14)Molar Refractivity: 48.78 cm3; (15)Molar Volume: 181.9 cm3; (16)Polarizability: 19.34×10-24cm3; (17)Surface Tension: 38.6 dyne/cm; (18)Enthalpy of Vaporization: 57.39 kJ/mol; (19)Vapour Pressure: 0.00229 mmHg at 25°C.

Uses of Pentanedioic acid,3-hydroxy-, 1,5-diethyl ester: it can be used to produce (R)-ethyl hydrogen-3-hydroxyglutarate. This reaction will need reagents a-chymotrypsin, aq. Na2HPO4.

You can still convert the following datas into molecular structure:
(1)SMILES: O=C(OCC)CC(O)CC(=O)OCC
(2)InChI: InChI=1/C9H16O5/c1-3-13-8(11)5-7(10)6-9(12)14-4-2/h7,10H,3-6H2,1-2H3
(3)InChIKey: OLLQYIBTJXUEEX-UHFFFAOYAA
(4)Std. InChI: InChI=1S/C9H16O5/c1-3-13-8(11)5-7(10)6-9(12)14-4-2/h7,10H,3-6H2,1-2H3
(5)Std. InChIKey: OLLQYIBTJXUEEX-UHFFFAOYSA-N

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 32328-03-3