Basic Information | Post buying leads | Suppliers |
Name |
Dimerin |
EINECS | N/A |
CAS No. | 125-64-4 | Density | 0.969g/cm3 |
PSA | 46.17000 | LogP | 1.45660 |
Solubility | 76g/L(25 oC) | Melting Point |
74-77° |
Formula | C10H17 N O2 | Boiling Point | 339.9°Cat760mmHg |
Molecular Weight | 183.25 | Flash Point | 143.1°C |
Transport Information | N/A | Appearance | N/A |
Safety | Poison by ingestion, subcutaneous, and intravenous routes. Moderately toxic by intraperitoneal routes. Human systemic effects by ingestion: general anesthesia, sleep disorder, motor activity and pulmonary changes. When heated to decomposition it emits toxic fumes of NOx. | Risk Codes | N/A |
Molecular Structure | Hazard Symbols | Abuse may cause addiction. | |
Synonyms |
2,4-Dioxo-3,3-diethyl-5-methylpiperidine;2,4-Dioxy-3,3-diethyl-5-methylpiperidine; 3,3-Diethyl-2,4-dioxo-5-methylpiperidine;3,3-Diethyl-5-methyl-2,4-piperidinedione; Dimerin; Methyprylon; Methyprylone;NSC 30442; Noctan; Nodular; Noludar; Ro 1-6463 |
IUPAC Name: 3,3-Diethyl-5-methylpiperidine-2,4-dione
Molecular Formula: C10H17NO2
Molecular Weight: 183.28g/mol
Density: 0.969g/cm3
EINECS: 204-745-4
Boiling Point: 339.9°C at 760mmHg
Flash Point: 143.1°C
Freely Rotating Bonds: 2
Polar Surface Area: 37.38 Å2
Index of Refraction: 1.441
Molar Refractivity: 49.93 cm3
Molar Volume: 189 cm3
Polarizability: 19.79 ×10-24 cm3
Surface Tension: 27.7 dyne/cm
Enthalpy of Vaporization: 58.34 kJ/mol
Vapour Pressure: 8.93E-05 mmHg at 25°C
The Cas Register Number of Dimerin is 125-64-4.The chemical synonyms of Dimerin (CAS NO.125-64-4) are Methyprylon ; Metiprilon ; Metiprilone ; Noludar ; Dimerin ; Noctan ; Methyprylone ; Methyprolon ; Maleate
Methyprylonum ; 3,3-Diethyl-5-methylpiperidine-2,4-dione ; 2,4-Dioxo-3,3-diethyl-5-methylpiperidine ; 3,3-Diethyl-2,4-dioxo-5-methylpiperidine .The molecular structure of Dimerin (CAS NO.125-64-4) is.
Dimerin (CAS NO.125-64-4) is used as hypnotic sedative.
1. | orl-wmn TDLo:600 mg/kg:CNS,PUL | JAMAAP JAMA, Journal of the American Medical Association. 198 (1966),1213. | ||
2. | orl-hmn TDLo:26 mg/kg:CNS | CTOXAO Clinical Toxicology. 6 (1973),563. | ||
3. | orl-rat LD50:860 mg/kg | 27ZQAG Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,264. | ||
4. | scu-rat LD50:400 mg/kg | 27ZQAG Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,264. | ||
5. | ivn-rat LD50:380 mg/kg | 27ZQAG Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,264. | ||
6. | orl-mus LD50:890 mg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 118 (1956),139. | ||
7. | ipr-mus LD50:1000 mg/kg | 27ZQAG Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,264. | ||
8. | ivn-mus LD50:275 mg/kg | 27ZQAG Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,264. | ||
9. | orl-dog LD50:300 mg/kg | CLDND* Compilation of LD50 Values of New Drugs .(J.R. MacDougal, Dept. of National Health and Welfare, Food and Drug Divisions,Ottawa, Ontario, Canada. |
Poison by ingestion, subcutaneous, and intravenous routes. Moderately toxic by intraperitoneal routes. Human systemic effects by ingestion: general anesthesia, sleep disorder, motor activity and pulmonary changes. When heated to decomposition it emits toxic fumes of NOx.
Dimerin (CAS NO.125-64-4) is a sedative of the piperidinedione derivative family. This medicine was used for treating insomnia, but is now rarely used as it has been replaced by newer drugs with fewer side effects, such as benzodiazepines.