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Dimethisterone and ethinyl estradiol

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Name

Dimethisterone and ethinyl estradiol

EINECS N/A
CAS No. 8015-19-8 Density N/A
PSA 77.76000 LogP 8.13130
Solubility N/A Melting Point N/A
Formula C23H32O2•C20H24O2 Boiling Point 479°C at 760 mmHg
Molecular Weight 636.99 Flash Point 203.5°C
Transport Information N/A Appearance N/A
Safety Suspected human carcinogen producing uterine tumors. Human reproductive effects by ingestion: abnormalities of the uterus, cervix, and vagina. A steroid. When heated to decomposition it emits acrid smoke and irritating fumes. Risk Codes N/A
Molecular Structure Molecular Structure of 8015-19-8 (Oracon) Hazard Symbols N/A
Synonyms

Oracon

 

Dimethisterone and ethinyl estradiol Chemical Properties

IUPAC Name: (8R,9S,13S,14S,17R)-17-Ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol; (6S,8R,9S,10R,13S,14S,17S)-17-hydroxy-6,10,13-trimethyl-17-prop-1-ynyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
Synonyms of Dimethisterone and ethinyl estradiol (CAS NO.8015-19-8): Ethinyl estradiol and dimethisterone ; Oracon ; Secrovin ; Androst-4-en-3-one, 17-beta-hydroxy-6-alpha-methyl-17-(1-propynyl)-, and 19-nor-17-alpha-pregna-1,3,5(10)-trien-20-yne-3,17-diol
CAS NO: 8015-19-8
Molecular Formula: C43H56O4
Molecular Weight: 636.9023
Molecular Structure : 
H bond acceptors: 2
H bond donors: 1
Freely Rotating Bonds: 1
Polar Surface Area: 26.3 Å2 
Flash Point: 203.5 °C
Enthalpy of Vaporization: 85.65 kJ/mol
Boiling Point: 479 °C at 760 mmHg
Vapour Pressure: 3.48E-11 mmHg at 25°C

Dimethisterone and ethinyl estradiol Toxicity Data With Reference

1.    

orl-wmn TDLo:244 mg/kg/8Y-I:CAR

    AJOGAH    American Journal of Obstetrics and Gynecology. 123 (1975),299.
2.    

orl-wmn TDLo:92 mg/kg/3Y-I:CAR

    OBGNAS    Obstetrics and Gynecology. 47 (1976),639.

Dimethisterone and ethinyl estradiol Safety Profile

Suspected human carcinogen producing uterine tumors. Human reproductive effects by ingestion: abnormalities of the uterus, cervix, and vagina. A steroid. When Dimethisterone and ethinyl estradiol (CAS NO.8015-19-8) is heated to decomposition ,it emits acrid smoke and irritating fumes.

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