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Cas Database |
| Name |
Eraldin |
EINECS | 229-712-1 |
| CAS No. | 6673-35-4 | Density | 1.127 g/cm3 |
| PSA | 70.59000 | LogP | 1.84660 |
| Solubility | N/A | Melting Point |
134-136° (BuOAc) |
| Formula | C14H22N2O3 | Boiling Point | 493.6 ºC at 760 mmHg |
| Molecular Weight | 266.34 | Flash Point | 252.3 ºC |
| Transport Information | N/A | Appearance | N/A |
| Safety | Poison by intravenous route. Moderately toxic by ingestion, subcutaneous, and intraperitoneal routes. An experimental teratogen. Human systemic effects by ingestion: eye damage, peritonitis, and dermatitis. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx. | Risk Codes | N/A |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
Acetanilide,4'-[2-hydroxy-3-(isopropylamino)propoxy]- (7CI,8CI);(?à)-Practolol;1-(4-Acetamidophenoxy)-3-isopropylamino-2-propanol;4'-[2-Hydroxy-3-(isopropylamino)propoxy]acetanilide;AY 21011;DL-4'-[2-Hydroxy-3-(isopropylamino)propoxy]acetanilide;Dalzic;Eraldin;ICI50172;N-[4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]acetamide;Practolol;Racemic Practolol;Teranol;dl-Practolol; |
Article Data | 14 |
Eraldin Consensus Reports
EPA Genetic Toxicology Program.
Eraldin Specification
Eraldin (CAS NO.6673-35-4), with the CAS registry number 6673-35-4, is also called 1-(4-Acetamidophenoxy)-3-isopropylamino-2-propanol ; 4'-(2-Hydroxy-3-(isopropylamino)propoxy)acetanilide ; AY 21011 ; Acetamide, N-(4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)phenyl)- ; CCRIS 1089 ; Dalzic ; ICI 50172 ; N-(4-(2-Hydroxy-3-((1-methylethyl)amino)propoxy)phenyl)acetamide ; Practolol ; Practololum [INN-Latin] ; Praktololu [Polish] ; Teranol ; UNII-SUG9176GRW . It is used as cardiovascular system drug.
Eraldin (CAS NO.6673-35-4) is poison by intravenous route. Moderately toxic by ingestion, subcutaneous, and intraperitoneal routes. An experimental teratogen. Human systemic effects by ingestion: eye damage, peritonitis, and dermatitis. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx. And Its toxic tabulation is:
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| man | TDLo | oral | 7550mg/kg/2Y (7550mg/kg) | SENSE ORGANS AND SPECIAL SENSES: CHANGES IN EXTRA-OCULAR MUSCLES: EYE GASTROINTESTINAL: PERITONITIS SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" | Medical Journal of Australia. Vol. 1, Pg. 44, 1975. |
| mouse | LD50 | intraperitoneal | 455mg/kg (455mg/kg) | LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Polish Journal of Pharmacology and Pharmacy. Vol. 25, Pg. 145, 1973. |
| mouse | LD50 | intravenous | 67400ug/kg (67.4mg/kg) | BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: ATAXIA | Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 20, Pg. 126, 1973. |
| mouse | LD50 | oral | 3661mg/kg (3661mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 20, Pg. 126, 1973. |
| mouse | LD50 | subcutaneous | 3357mg/kg (3357mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 20, Pg. 126, 1973. |
| rat | LD50 | intraperitoneal | 540mg/kg (540mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 20, Pg. 126, 1973. |
| rat | LD50 | intravenous | 130mg/kg (130mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 20, Pg. 126, 1973. |
| rat | LD50 | oral | 3458mg/kg (3458mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 20, Pg. 126, 1973. |
| rat | LD50 | subcutaneous | 7500mg/kg (7500mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 20, Pg. 126, 1973. |
| women | TDLo | oral | 4mg/kg (4mg/kg) | SENSE ORGANS AND SPECIAL SENSES: CONJUNCTIVE IRRITATION: EYE SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE | British Medical Journal. Vol. 1, Pg. 595, 1975. |
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