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Ethamivan

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Name

Ethamivan

EINECS N/A
CAS No. 304-84-7 Density 1.115g/cm3
PSA 49.77000 LogP 1.88280
Solubility N/A Melting Point 96-97 °C

Formula C12H17 N O3 Boiling Point 401.4°Cat760mmHg
Molecular Weight 223.272 Flash Point 196.6°C
Transport Information N/A Appearance N/A
Safety Poison by ingestion, intravenous, subcutaneous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx. Risk Codes 25
Molecular Structure Molecular Structure of 304-84-7 (ETHAMIVAN) Hazard Symbols
Synonyms

Vanillamide,N,N-diethyl- (6CI,7CI,8CI); 3-Methoxy-4-hydroxybenzoic acid diethylamide;Analepticon; Cardiovanil; Corivanil; Diethamivan; Diethylvanillamide; Emivan;Etamivan; Etamivanum; Ethamivan; N,N-Diethyl-4-hydroxy-3-methoxybenzamide;N,N-Diethylvanillamide; NSC 406087; Romecor; Sevanil; Simaron; Vandid; Vanillicacid N,N-diethylamide; Vanillic acid diethylamide; Vanillic diethylamide;Ventilone

 

Ethamivan Chemical Properties

Product Name: Ethamivan (CAS NO.304-84-7)


Molecular Formula: C12H17NO3
Molecular Weight: 223.27g/mol
Mol File: 304-84-7.mol
Einecs: 206-157-3
Melting Point: 96-97 °C
Boiling point: 401.4 °C at 760 mmHg
Flash Point: 196.6 °C
Density: 1.115 g/cm3
Solubility: methanol: 0.1 g/mL, clear
Surface Tension: 41.8 dyne/cm
Enthalpy of Vaporization: 67.78 kJ/mol
Vapour Pressure: 5.11E-07 mmHg at 25°C
XLogP3-AA: 2.1
H-Bond Donor: 1
H-Bond Acceptor: 3
Structure Descriptors of Ethamivan (CAS NO.304-84-7):
  IUPAC Name: N,N-diethyl-4-hydroxy-3-methoxybenzamide
  Canonical SMILES: CCN(CC)C(=O)C1=CC(=C(C=C1)O)OC
  InChI: InChI=1S/C12H17NO3/c1-4-13(5-2)12(15)9-6-7-10(14)11(8-9)16-3/h6-8,14H,4-5H2,1-3H3 
  InChIKey: BQJODPIMMWWMFC-UHFFFAOYSA-N

Ethamivan Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 intravenous 30mg/kg (30mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 377, 1972.
dog LD50 oral 300mg/kg (300mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 377, 1972.
mouse LD50 intraperitoneal 38mg/kg (38mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT

BEHAVIORAL: REGIDITY
Research Progress in Organic-Biological and Medicinal Chemistry. Vol. 1, Pg. 423, 1964.
mouse LD50 intravenous 15mg/kg (15mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 377, 1972.
mouse LD50 oral 67mg/kg (67mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT

BEHAVIORAL: REGIDITY
Research Progress in Organic-Biological and Medicinal Chemistry. Vol. 1, Pg. 423, 1964.
mouse LD50 subcutaneous 57mg/kg (57mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT

BEHAVIORAL: REGIDITY
Research Progress in Organic-Biological and Medicinal Chemistry. Vol. 1, Pg. 423, 1964.
rat LD50 intraperitoneal 28mg/kg (28mg/kg)   Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. Vol. 243, Pg. 609, 1956.
rat LD50 intravenous 17mg/kg (17mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Acta Biologica et Medica Germanica. Vol. 9, Pg. 67, 1962.
rat LD50 oral 154mg/kg (154mg/kg)   Annales Pharmaceutiques Francaises. Vol. 17, Pg. 41, 1959.

Ethamivan Safety Profile

Poison by ingestion, intravenous, subcutaneous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx.
Safety Information of Ethamivan (CAS NO.304-84-7):
Hazard Codes: TToxic
Risk Statements: 25 
25:  Toxic if swallowed 
Safety Statements: 36/37/39-45
36:  Wear suitable protective clothing  
37:  Wear suitable gloves 
39:  Wear eye/face protection 
45:  In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) 

Ethamivan Specification

 Ethamivan ,its CAS NO. is 304-84-7,the synonyms is Analepticon ; BRN 2694478 ; Benzamide, N,N-diethyl-4-hydroxy-3-methoxy- ; Cardiovamil ; Corivanil ; Diethamivan ; Diethylamide de vanillique ; Diethylvanillamide ; EINECS 206-157-3 ; Etamivanum ; N,N-Diethylvanillamide ; NSC 406087 ; Romecor ; Sevanil ; Simaron ; UNII-M44O63YPV9 ; Vandid ; Vanillic acid N,N-diethylamide ; Vanillic acid diethylamide ; Vanillinsaeure-diaethylamid ; Ventilone .

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