- 36330-86-6Benzenebutanoic acid, g-oxo-4-phenoxy-
- 36331-57-4Benzenemethanesulfonicacid, hydrazide
- 3633-17-8Hexanoicacid, 6-amino-, ethyl ester, hydrochloride (1:1)
- 36333-48-9Arsonic acid, tridecyl-(9CI)
- 36335-67-8Phosphoramidothioicacid, N-(1-methylpropyl)-, O-ethyl O-(5-methyl-2-nitrophenyl) ester
- 36338-96-24-Cyclohexene-1,3-dione,6-b-D-glucopyranosyl-2-[[(3S)-3-b-D-glucopyranosyl-2,3,4-trihydroxy-5-[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propen-1-yl]-6-oxo-1,4-cyclohexadien-1-yl]methylene]-5,6-dihydroxy-4-[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propen-1-yl]-,(2Z,6S)-
- 36339-04-5b-Alanine,N-[5-(acetylamino)-2-methoxyphenyl]-, 2-methoxyethyl ester
- 36340-61-12-Pyridinamine,4-chloro-6-methyl-
- 36342-07-12-Butenoic acid,4-oxo-4-(propylamino)-, (2Z)-
- 36343-81-4Bis(oxiran-2-ylmethyl) cyclohex-4-ene-1,2-dicarboxylate
Hot Products
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
- 7631-86-9Silicon dioxide
- 302-79-4Tretinoin
- 77-92-9Citric acid
|
Basic Information |
|
Post buying leads |
|
Suppliers |
|
Cas Database |
| Name |
Fenbufen |
EINECS | 252-979-0 |
| CAS No. | 36330-85-5 | Density | 1.188 g/cm3 |
| PSA | 54.37000 | LogP | 3.40110 |
| Solubility | 2.212mg/L(25 oC) | Melting Point |
184-187 °C(lit.) |
| Formula | C16H14O3 | Boiling Point | 470.2 °C at 760 mmHg |
| Molecular Weight | 254.285 | Flash Point | 252.3 °C |
| Transport Information | UN 2811 6.1/PG 3 | Appearance | White solid |
| Safety | 28-45 | Risk Codes | 25 |
| Molecular Structure |
|
Hazard Symbols |
 T
|
| Synonyms |
Propionicacid, 3-(4-biphenylylcarbonyl)- (6CI);3-(4-Biphenylcarbonyl)propionic acid;3-(4-Phenylbenzoyl)propionic acid;3-[(Biphenyl-4-yl)carbonyl]propionic acid;4-(4-Phenylphenyl)-4-oxobutyric acid;4-(Biphenyl-4-yl)-4-oxobutanoic acid;Bufemid;CL 82204;Cinopal;Cinopol;Lederfen;Napanol;g-Oxo[1,1'-biphenyl]-4-butanoicacid;[1,1'-Biphenyl]-4-butanoicacid, g-oxo-; |
Article Data | 54 |
Fenbufen Chemical Properties
Molecular Formula: C16H14O3
Molecular Weight: 254.28
EINECS: 252-979-0
Density: 1.188 g/cm3
Flash Point: 252.3 °C
Appearance: White Solid
Index of Refraction: 1.585
CAS Registry Number: 36330-85-5
Melting Point: 184-187 °C(lit.)
Enthalpy of Vaporization: 77.19 kJ/mol
Boiling Point: 470.2 °C at 760 mmHg
Vapour Pressure: 1.21E-09 mmHg at 25 °C
IUPAC Name: 4-Oxo-4-(4-phenylphenyl)butanoic acid
Synonyms: Fenbufen ; Gamma-oxo-[1,1'-biphenyl]-4-butanoic acid ; 4-(4-Biphenyl)-4-oxobutyric acid ; 3-(4-phenylbenzoyl)propionic acid ; 1’-(biphenyl)-4-butanoicacid,gamma-oxo- ; 3-(4-Biphenylylcarbonyl)-propionicacid
Following is the molecular structure of 3-(4-Biphenylylcarbonyl)-propionic acid (CAS NO.36330-85-5):
.gif)
Fenbufen Uses
3-(4-Biphenylylcarbonyl)-propionic acid (CAS NO.36330-85-5) is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis. It can also be used to relieve backaches, sprains, and fractures. 3-(4-Biphenylylcarbonyl)-propionic acid is available as a capsule or tablet sold with the brand names Cepal, Cinopal, Cybufen, Lederfen, and Reugast. 3-(4-Biphenylylcarbonyl)-propionic acid (CAS NO.36330-85-5) acts by preventing cyclooxygenase from producing the prostaglandins that cause inflammation.
Fenbufen Production
Producte method: In the presence of anhydrous aluminum chloride, biphenyl, and succinic anhydride in nitrobenzene in the condensation, the system was fenbufen, the yield was 70%.
Fenbufen Toxicity Data With Reference
| 1. | orl-wmn TDLo:12 mg/kg/1D-I | BMJOAE British Medical Journal. 290 (1985),822. | ||
| 2. | orl-man TDLo:90 mg/kg/1W-I:PUL | HUTODJ Human Toxicology. 7 (1988),35. | ||
| 3. | orl-rat LD50:200 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 30 (1980),725. | ||
| 4. | ipr-rat LD50:265 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 30 (1980),721. | ||
| 5. | scu-rat LD50:247 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 30 (1980),721. | ||
| 6. | orl-mus LD50:795 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 30 (1980),721. | ||
| 7. | ipr-mus LD50:482 mg/kg | PCIPDV Beijing Yixueyuan Xuebao. Journal of Peking Medical College. 15 (1983),132. | ||
| 8. | scu-mus LD50:1189 mg/kg | IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 10 (1979),884. |
Fenbufen Safety Profile
Poison by ingestion, intraperitoneal, and subcutaneous routes. Human systemic effects by ingestion: cough, sweating, body temperature. An experimental teratogen. Other experimental reproductive effects. An anti-inflammatory agent. When heated to decomposition it emits acrid smoke and irritating fumes.
Safety Information of 3-(4-Biphenylylcarbonyl)-propionic acid (CAS NO.36330-85-5):
Hazard Codes: T 
Risk Statements: 25
R25: Toxic if swallowed.
Safety Statements: 28-45
S28: After contact with skin, wash immediately with plenty of soap-suds.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: DV1761000
HazardClass: 6.1
PackingGroup: III
What can I do for you?
Get Best Price
