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Fluderma

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Fluderma

EINECS N/A
CAS No. 2825-60-7 Density 1.33g/cm3
PSA 108.36000 LogP 3.96280
Solubility N/A Melting Point 180-182°
Formula C29H38 Cl F O8 Boiling Point 683.7°Cat760mmHg
Molecular Weight 569.067 Flash Point 367.3°C
Transport Information N/A Appearance N/A
Safety Moderately toxic by intraperitoneal and subcutaneous routes. Used as a glucocorticoid (a corticosteroid which affects carbohydrate, protein and fat metabolism with many other side effects). When heated to decomposition it emits very toxic fumes of F and Cl. Risk Codes N/A
Molecular Structure Molecular Structure of 2825-60-7 (formocortal) Hazard Symbols N/A
Synonyms

Pregna-3,5-diene-6-carboxaldehyde,3-(2-chloroethoxy)-9-fluoro-11b,16a,17,21-tetrahydroxy-20-oxo-,cyclic 16,17-acetal with acetone, 21-acetate (7CI,8CI);3H-Naphth[2',1':4,5]indeno[1,2-d][1,3]dioxole,pregna-3,5-diene-6-carboxaldehyde deriv.; 3-(2-Chloroethoxy)-6-formyl-9a-fluoropregna-3,5-diene-11b,16a,17,21-tetrol-20-one 21-acetate 16a,17a-acetonide; 3-(2-Chloroethoxy)-9-fluoro-11b,16a,17,21-tetrahydroxy-20-oxo-3,5-pregnadiene-6-carboxaldehydecyclic 16,17-acetal with acetone 21-acetate; 3-(2-Chloroethoxy)-9a-fluoro-6-formyl-11b,21-dihydroxy-16a,17a-isopropylidenedioxypregna-3,5-dien-20-one;3-(2'-Chloroethoxy)-6-formyl-9a-fluoro-11b,16a,17a,21-tetrahydroxypregna-3,5-diene-20-one16,17-acetonide, 21-acetate; Cortocin F; Cutisterol; Deflamene; Deflamin;Dermacort; FI 6341; Fluderma; Fluoformylon; Fluoroformylon; Fluoroformylone;Formocortal; NSC 150527

Article Data 1

Fluderma Chemical Properties

Product Name: Fluderma
Synonyms of Fluderma (CAS NO.2825-60-7) : 3-(2'-Chloroethoxy)-6-formyl-9alpha-fluoro-11beta,16alpha,17alpha,21-tetrahydroxypregna-3,5-diene-20-one 16,17-acetonide, 21-acetate ; 3-(2-Chloroethoxy)-9alpha-fluoro-6-formyl-11beta,21-dihydroxy-16alpha,17alpha-isopropylidenedioxypregna-3,5-dien-20-one ; Cortocin F ; Deflamene ; Formoftil ; Pregna-3,5-diene-6-carboxaldehyde, 21-(acetyloxy)-3-(2-chloroethoxy)-9-fluoro-11-hydroxy-16,17-((1-methylethylidene)bis(oxy))-20-oxo-, (11beta,16alpha)-
InChI: InChI=1/C29H38ClFO8/c1-16(33)37-15-23(35)29-24(38-25(2,3)39-29)12-20-21-10-17(14-32)19-11-18(36-9-8-30)6-7-26(19,4)28(21,31)22(34)13-27(20,29)5/h11,14,20-22,24,34H,6-10,12-13,15H2,1-5H3/t20-,21-,22-,24+,26-,27-,28-,29+/m0/s1
CAS NO:2825-60-7
Molecular Formula:C29H38ClFO8
Molecular Weight :569.0586
Molecular Structure :
Index of Refraction:1.564
Surface Tension: 51.7 dyne/cm
Density: 1.33 g/cm3
Flash Point: 367.3 °C
Enthalpy of Vaporization: 114.7 kJ/mol
Boiling Point: 683.7 °C at 760 mmHg
Vapour Pressure: 1.21E-21 mmHg at 25°C

Fluderma Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 537mg/kg (537mg/kg)   Journal Europeen de Toxicologie. Vol. 4, Pg. 88, 1971.
mouse LD50 subcutaneous 490mg/kg (490mg/kg)   Journal Europeen de Toxicologie. Vol. 4, Pg. 88, 1971.

Fluderma Safety Profile

Moderately toxic by intraperitoneal and subcutaneous routes. Used as a glucocorticoid (a corticosteroid which affects carbohydrate, protein and fat metabolism with many other side effects). When Fluderma (CAS NO.2825-60-7) is heated to decomposition, it emits very toxic fumes of F and Cl.

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