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Name |
Fluderma |
EINECS | N/A |
CAS No. | 2825-60-7 | Density | 1.33g/cm3 |
PSA | 108.36000 | LogP | 3.96280 |
Solubility | N/A | Melting Point |
180-182° |
Formula | C29H38 Cl F O8 | Boiling Point | 683.7°Cat760mmHg |
Molecular Weight | 569.067 | Flash Point | 367.3°C |
Transport Information | N/A | Appearance | N/A |
Safety | Moderately toxic by intraperitoneal and subcutaneous routes. Used as a glucocorticoid (a corticosteroid which affects carbohydrate, protein and fat metabolism with many other side effects). When heated to decomposition it emits very toxic fumes of F− and Cl−. | Risk Codes | N/A |
Molecular Structure | Hazard Symbols | N/A | |
Synonyms |
Pregna-3,5-diene-6-carboxaldehyde,3-(2-chloroethoxy)-9-fluoro-11b,16a,17,21-tetrahydroxy-20-oxo-,cyclic 16,17-acetal with acetone, 21-acetate (7CI,8CI);3H-Naphth[2',1':4,5]indeno[1,2-d][1,3]dioxole,pregna-3,5-diene-6-carboxaldehyde deriv.; 3-(2-Chloroethoxy)-6-formyl-9a-fluoropregna-3,5-diene-11b,16a,17,21-tetrol-20-one 21-acetate 16a,17a-acetonide; 3-(2-Chloroethoxy)-9-fluoro-11b,16a,17,21-tetrahydroxy-20-oxo-3,5-pregnadiene-6-carboxaldehydecyclic 16,17-acetal with acetone 21-acetate; 3-(2-Chloroethoxy)-9a-fluoro-6-formyl-11b,21-dihydroxy-16a,17a-isopropylidenedioxypregna-3,5-dien-20-one;3-(2'-Chloroethoxy)-6-formyl-9a-fluoro-11b,16a,17a,21-tetrahydroxypregna-3,5-diene-20-one16,17-acetonide, 21-acetate; Cortocin F; Cutisterol; Deflamene; Deflamin;Dermacort; FI 6341; Fluderma; Fluoformylon; Fluoroformylon; Fluoroformylone;Formocortal; NSC 150527 |
Article Data | 1 |
Product Name: Fluderma
Synonyms of Fluderma (CAS NO.2825-60-7) : 3-(2'-Chloroethoxy)-6-formyl-9alpha-fluoro-11beta,16alpha,17alpha,21-tetrahydroxypregna-3,5-diene-20-one 16,17-acetonide, 21-acetate ; 3-(2-Chloroethoxy)-9alpha-fluoro-6-formyl-11beta,21-dihydroxy-16alpha,17alpha-isopropylidenedioxypregna-3,5-dien-20-one ; Cortocin F ; Deflamene ; Formoftil ; Pregna-3,5-diene-6-carboxaldehyde, 21-(acetyloxy)-3-(2-chloroethoxy)-9-fluoro-11-hydroxy-16,17-((1-methylethylidene)bis(oxy))-20-oxo-, (11beta,16alpha)-
InChI: InChI=1/C29H38ClFO8/c1-16(33)37-15-23(35)29-24(38-25(2,3)39-29)12-20-21-10-17(14-32)19-11-18(36-9-8-30)6-7-26(19,4)28(21,31)22(34)13-27(20,29)5/h11,14,20-22,24,34H,6-10,12-13,15H2,1-5H3/t20-,21-,22-,24+,26-,27-,28-,29+/m0/s1
CAS NO:2825-60-7
Molecular Formula:C29H38ClFO8
Molecular Weight :569.0586
Molecular Structure :
Index of Refraction:1.564
Surface Tension: 51.7 dyne/cm
Density: 1.33 g/cm3
Flash Point: 367.3 °C
Enthalpy of Vaporization: 114.7 kJ/mol
Boiling Point: 683.7 °C at 760 mmHg
Vapour Pressure: 1.21E-21 mmHg at 25°C
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 537mg/kg (537mg/kg) | Journal Europeen de Toxicologie. Vol. 4, Pg. 88, 1971. | |
mouse | LD50 | subcutaneous | 490mg/kg (490mg/kg) | Journal Europeen de Toxicologie. Vol. 4, Pg. 88, 1971. |
Moderately toxic by intraperitoneal and subcutaneous routes. Used as a glucocorticoid (a corticosteroid which affects carbohydrate, protein and fat metabolism with many other side effects). When Fluderma (CAS NO.2825-60-7) is heated to decomposition, it emits very toxic fumes of F− and Cl−.