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Despite a large number of acridine derivatives have already
been studied as anticancer agents (Denny, 2002; Sebestik et al.,
2007; Gálvez-Peralta et al., 2009; Guo et al., 2009; Gurova, 2009;
Neznanov et al., 2009), the present cytotoxic compounds contain
novel, unexplored structural features whose relevance in the field
deserve investigation.
Acknowledgments
Financial support from BIOMEDICINE PROJECT is gratefully
acknowledged. The authors thank O. Gagliardo for performing
the elemental analyses.
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