Research on Chemical Intermediates p. 1691 - 1697 (2012)
Update date:2022-08-04
Topics:
Li, Zhenghua
Xiao, Shangyou
Liang, Ronghui
Xia, Zhining
In hydrothermal reactions at 150-180 °C, 2-(arylamino)nicotinic acids were synthesized by amination of 2-chloronicotinic acid with aromatic amine derivatives, with potassium carbonate as base. The procedure is efficient, environmentally friendly, and practical, with moderate to excellent yields (up to 98%). Springer Science+Business Media B.V. 2012.
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