Synthesis p. 37 - 40 (1986)
Update date:2022-09-26
Topics:
Seebach, Dieter
Eberle, Martin
Reduction of ethyl 4-t-butoxy-3-oxobutanoate with fermenting yeats yields (R)-ethyl 4-t-butoxy-3-hydroxybutanoate in 97percent e.e.Since the protective group is readily removed from the product of reduction, the present procedure provides a simple entry to the "world of chiral blocks" formally derived from (R)-malic acid.
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Doi:10.1002/chem.200900536
(2009)Doi:10.1021/ol801666w
(2008)Doi:10.1055/s-1986-31601
(1986)Doi:10.1016/S0040-4020(01)87734-6
(1987)Doi:10.1021/ja508371q
(2015)Doi:10.1016/S0040-4039(00)80659-0
(1988)