Organic Letters
Letter
(11) For a discussion on issues associated with the scale-up of the
photochemical reaction, see: (a) Tucker, J. W.; Zhang, Y.; Jamison, T.
F.; Stephenson, C. R. J. Angew. Chem., Int. Ed. 2012, 51, 4144.
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(12) (a) Cassiano. N. M. In Alkaloids: Properties, Applications and
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(b) Newman, D. J.; Cragg, G. M. J. Nat. Prod. 2012, 75, 311.
ASSOCIATED CONTENT
* Supporting Information
Experimental procedures and characterization data of all new
compounds. This material is available free of charge via the
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(13) For a recent review, see: Wang, J.; Sanchez-Rosello, M.; Acena,
J. L.; del Pozo, C.; Sorochinsky, A. E.; Fustero, S.; Soloshonok, V. A.;
Liu, H. Chem. Rev. 2014, 114, 2432.
(14) Hughes, G.; Devine, P. N.; Naber, J. R.; O’Shea, P. D.; Foster, B.
S.; McKay, D. J.; Volante, R. P. Angew. Chem., Int. Ed. 2007, 46, 1839.
(15) Hoffman, M. Z.; Hayon, E. J. Am. Chem. Soc. 1972, 94, 7950.
For a recent review on thyil radicals, see: Denes, F.; Pichowicz, M.;
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Povie, G.; Renaud, P. Chem. Rev. 2014, 114, 2587.
(16) For an example on the use of phenyl disulfide as an electron
acceptor in a single electron transfer reaction, see: Taniguchi, T.; Fujii,
T.; Idota, A.; Ishibashi, H. Org. Lett. 2009, 11, 3298.
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AUTHOR INFORMATION
Corresponding Author
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Author Contributions
†These authors contributed equally.
Notes
The authors declare no competing financial interest.
ACKNOWLEDGMENTS
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The Olle Engkvist Byggmastare foundation is gratefully
acknowledged for financial support. Prof. Dr. Per-Ola Norrby
̈
at AstraZeneca (Pharmaceutical Development, Global Medi-
cines Development, Molndal, Sweden) is gratefully acknowl-
̈
edged for valuable and inspiring discussions.
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