Bioorganic and Medicinal Chemistry Letters p. 1587 - 1592 (1999)
Update date:2022-09-26
Topics:
Chen
Goel
Hyun
Magano
Rubin
The title compound 1 is a potent interleukin-1β-converting enzyme (ICE) inhibitor. Recently, an efficient chiral synthesis of compound 1 has been accomplished in our labs. The overall yield of this 18-step stereoselective synthesis was 9.8%.
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