10.1002/anie.201708693
Angewandte Chemie International Edition
COMMUNICATION
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In conclusion, we have developed a powerful and selective
strategy for the amination of aromatics via aminium radicals.
This approach provides fast access to aryl amines using un-
functionalized aromatics in just 15 minutes. The generality of the
process has been illustrated through the late-stage modification
of chiral catalyst templates, blockbuster drugs, natural products
and photo-switches.
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Acknowledgements
D. L. thanks the European Union for a Career Integration Grant
(PCIG13-GA-2013-631556) and EPSRC for a research grant
(EP/P004997/1). A. R. thanks the Marie Curie Actions for a
Fellowship (703238).
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Keywords: aryl amine • aminium radicals • N-arylation • late-
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