P.M. Reddy et al. / Spectrochimica Acta Part A 70 (2008) 1231–1237
1237
the newly synthesized ruthenium organometallics were used
as catalysts in the present investigations. The hydrolysis time
was monitored by determining the produced amount of nico-
tinic acid (Scheme 3) with conductometric titration using 0.1N
sodium hydroxide. It was observed that the present catalysts
are able to successfully hydrolyze EF within 20 min. The per-
cent yields of NA were found to be in the range of 98.6–99.1%
(Table 4).
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5. Conclusions
[14] M. Ashok, V. Ravinder, A.V.S.S. Prasad, Transit. Metal Chem. 32 (2007)
23.
Based on the infrared, 1H, 13C NMR and mass spectral data it
is found that, the Ru(II) metal center is occupied by COD, chlo-
ride ions, tertiary phosphines and carbonmonoxide groups. In all
the organometallics, the two chloride atoms are arranged in cis
position whereas in 2a–f and 3a–f organometallics the two phos-
phine ligands are present in the trans position around the metal
centre as evidenced by 31P NMR. The structures are proposed
tentativelyasoctahedralforalltheaboveRu(II)organometallics.
These organometallics are found to be efficient catalysts in the
hydrolysis of etofibrate. This method is simple to set-up, requires
short reaction times and produces high product yields.
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