Journal of Medicinal Chemistry p. 374 - 383 (1988)
Update date:2022-09-26
Topics: Experimental Design Structural parameters μ and δ opioid receptors Enkephalin-related peptides Discrimination Ligand-receptor interaction
Gacel
Zajac
Delay-Goyet
Dauge
Roques
The previous rules proposed for selective recognition of μ and δ opioid receptors by modified enkephalins were investigated through an extensive structure-activity study. Thus, modifications of the sequence of TRIMU 4 (Tyr-D-Ala-Gly-NHCH(CH3)CH
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