Journal of Medicinal Chemistry p. 902 - 906 (1988)
Update date:2022-08-04
Topics: Synthesis Activity antihypertensive Vasodilator Thiadiazoles 2-Aryl-5-hydrazino-1,3,4-thiadiazoles
Turner, Stephen
Myers, Malcolm
Gadie, Brian
Nelson, Anthony J.
Pape, Robin
et al.
Some 2-Aryl-5-hydrazino-1,3,4-thiadiazoles have been synthesized and screened for antihypertensive activity.In general, compounds with a 2-substituted phenyl ring had higher activity than their 3- or 4-substituted counterparts or those containing heteroar
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