Journal of Organic Chemistry p. 1496 - 1500 (1993)
Update date:2022-08-04
Topics: Synthesis Metabolite biologically active Vitamine-D2
Choudhry, Satish C.
Belica, Peter S.
Coffen, David L.
Focella, Antonino
Maehr, Hubert
et al.
The synthesis of 1α,25,28-trihydroxyvitamin-D2 (1) from vitamin-D2 is described.Approaches to the upper side-chain synthon via the chiral sulfone 15, prepared either through the enzymatic resolution of 10 or the opening of the optica
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