Tetrahedron p. 2769 - 2778 (1987)
Update date:2022-08-03
Topics:
Epifani, Erbana
Florio, Saverio
Ingrosso, Giovanni
Sgarra, Riccardo
Stasi, Francesca
Mono- and bis-addition reactions of the β,γ-unsaturated Grignard reagents 2 and 6 to the C=N bonds of quinoxalines 1 afford high yields of dihydroquinoxalines 4 and tetrahydroquinoxalines 3.Dehydrogenation of 4g-l and 3a-c with DDQ leads to allylic quinoxalines 1i-m and 1e-g respectively in very good yields.Allylic and propargylic quinoxalines 1m and 1s can conveniently be synthesized by "cross-coupling" of 2-chloro-3-methylquinoxaline with 2c and 6a.
View MoreContact:+44 (0)161 367 9441
Address:
Yueyang Hudex Pharmaceuticals Ltd.
Contact:0730-8748800
Address:Wujiang Bridge,Yueyang Economy & Technology Development Zone
Taizhou Chenyi chemical co. LTD,
Contact:13736652831
Address:NO.273 SHANGHAI SOUTH STREET,LUQIAO DISTRICT,ZHEJIANG PROVINCE,CHINA.
BAODING SINO-CHEM INDUSTRY CO.,LTD
Contact:0312-5956088
Address:NO.8 FUXING ROAD,CHINA
Nanjing Spring & Autumn Biological Engineering Co., Ltd.
Contact:86-18051083338
Address:Suite# 210, No. 1 BuildingNanjing Agricultural Biotechnology High-tech Entrepreneurship Center, No. 4 Tongwei Road, Xuanwu District, Nanjing,China
Doi:10.1016/0223-5234(87)90263-7
(1987)Doi:10.1021/jo00243a050
(1988)Doi:10.1021/ja00215a066
(1988)Doi:10.1007/s10600-005-0017-y
(2004)Doi:10.1021/ja01307a052
()Doi:10.1021/ja00218a060
(1988)