Synthesis p. 18 - 20 (1991)
Update date:2022-08-05
Topics:
Murray
Wachter
Barton
Forero-Kelly
Tepoxalin, a potent anti-inflammatory agent, and its analogs can be synthesized by condensing an appropriate arylhydrazine hydrochloride and a 6-aryl-4,6-dioxohexanoic acid in alcohol with a base catalyst. These diarylpyrazolylpropanoic acids can be converted to their N-methylhydroxamic acids by generating the requisite acid chloride, and allowing it to react with N-methylhydroxylamine.
View MoreHangzhou Kai Peng Biotechnology Co., Ltd.
Contact:86-571-89939007
Address:NO. 499, Wensan West Road, Xihu District, Hangzhou, 310012, China
Contact:+86-025-52406782
Address:8 Taizishan Rd., Yanjiang Industrial Development Area, Nanjing, Jiangsu, China.
Hangzhou Yanshan Chemical Co.,Ltd.
Contact:86-571- 87698076
Address:Room 1001, #1 Building, Zhongtian MCC, No.2 Youzhinong, Wenyi West Road, Xihu District, Hangzhou, China
Huangshi Shennong Chemical Technology Co., Ltd
Contact:+86-714-3072290
Address:Eastern industrial park , Tieshan district , Huangshi city ,Hubei province , China
Chengdu Boon Stream Chemical Industry Co.,Ltd.
Contact:+86-28-83156758
Address:No.859,Dongzikou Road,Jinniu District,Chengdu,Sichuan,P.R.China
Doi:10.1016/j.tetlet.2009.01.043
(2009)Doi:10.1002/jccs.199800079
(1998)Doi:10.1016/0022-328X(87)80255-3
(1987)Doi:10.1021/ja00218a068
(1988)Doi:10.1016/j.tetlet.2009.01.052
(2009)Doi:10.1080/10587250108025704
(2001)