Organic process research and development p. 261 - 273 (2020)
Update date:2022-07-29
Topics:
Bednarz, Mark S.
Iimura, Shinya
Kanamarlapudi, Ramanaiah C.
Lim, Ngiap-Kie
Wu, Wenxue
Yan, Jie
Zhang, Haiming
Zhao, Matthew M.
Two process routes for LX1031, a tryptophan hydroxylase inhibitor for the treatment of irritable bowel syndrome, were developed. They shared the same left-hand and right-hand starting materials as well as the penultimate intermediate. The chiral center in
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(2021)