Synthetic Communications p. 2683 - 2693 (2009)
Update date:2022-09-26
Topics:
Thienthong, Neeranat
Bergman, Ylva E.
Perlmutter, Patrick
An extremely simple method for preparing imines from aryl and alkylaryl ketones and a variety of amines is presented. The process involves the diffusion of the appropriate amine vapor from one arm of an H-tube into the other arm containing the ketone. Most reactions are quantitative, and, in many cases, there is no real work-up or purification required.
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