Chemistry of Heterocyclic Compounds p. 765 - 771 (1988)
Update date:2022-07-30
Topics:
Kononov, L. I.
Veinberg, G. A.
Liepin'sh, E. E.
Dipan, I. V.
Sukhova, N. M.
Lukevits, E.
Ethyl ester derivatives of 6- and 8-substituted 2-methyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids have been synthesized by treatment of the diethyl ester of acetylmalonic acid with 2- or 4-substituted anilines.Condensation of these newly synthesized quinolinecarboxylic acid derivatives with 4-nitrobenzaldehyde resulted in the formation of 6- and 8-substituted 2-<2-(4-nitrophenyl)vinyl>-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids and ethyl esters of 6- and 8-substituted 2-<2-(4-nitrophenyl)vinyl>-4-acetoxy-3-quinolinecarboxylic acids.The tautomeric and conformational transformations of these newly synthesized compounds have also been investigated, using IR, NMR, and UV spectroscopy.
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Doi:10.1002/chem.201000738
(2010)Doi:10.1007/BF01169946
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(2010)