Tetrahedron Letters p. 7101 - 7104 (1998)
Update date:2022-08-03
Topics:
Seong, Mi Ra
Song, Hyun Nam
Kim, Jae Nyoung
N-Tosylated phenylalanine derivatives in benzene in the presence of sulfuric acid afforded 2-arylnaphthalene derivatives in moderate yields. The reaction might proceed via the corresponding decarbonylated N-tosylimine derivatives. Aldol type reaction of N-tosylimines followed by intramolecular Friedel-Crafts reaction and elimination of p-toluenesulfonamide gave 2- arylnaphthalenes.
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