Tetrahedron Letters p. 297 - 300 (1989)
Update date:2022-09-26
Topics:
Miller, R. Bryan
Dugar, Sundeep
Ellipticine, a 6H-pyrido<4,3-b>carbazole alkaloid, has been regiospecifically synthesized by a general route which should allow for the preparation of a number of derivatives.The approach employs a versatile coupling reaction between phenylboronic acid and a substituted bromoisoquinoline followed by carbazole ring formation via a nitrene insertion reaction to give ellipticine.
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