were synthesized in good yields. Furthermore, the scope of
this process was successfully extended to the synthesis of 2-
aminobenzoxazoles from the reaction of isothiocyanate with
2-aminophenol by using an inexpensive and environmentally be-
nign iron catalyst. Compared with literature methods, this novel
synthetic approach has advantages such as a high efficiency,
readily available starting materials, a highly simple and practical
procedure, and an economically- as well as environmentally-
sustainable nature. Work to study the detailed mechanism and
find further applications of the synthetic protocol developed in
this paper are currently under way.
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This work was financially supported by the National Natural
Science Foundation of China (nos. 20772025 and 20972042),
the Innovation Scientists and Technicians Troop Construction
Projects of Henan Province (no. 104100510019) and the Program
for Science & Technology Innovation Talents in Universities of
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