Journal of Medicinal Chemistry p. 2408 - 2412 (1990)
Update date:2022-08-05
Topics: Synthesis N-substituted derivatives Dopamine Receptor Affinities 2-(4-fluoro-3-hydroxyphenyl)ethylamine
Claudi, Francesco
Cardellini, Mario
Cingolani, Gian Mario
Piergentili, Alessandro
Pertuzzi, Guidubaldo
Balduini, Walter
The synthesis of 2-(4-fluoro-3-hydroxyphenyl)ethylamine (26) and of some N,N-dialkyl derivatives (27-30) starting from 4-fluoro-3-hydroxytoluene and their in vitro binding affinities for dopamine (DA) receptor are reported.The amine 26 can be regarded as
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