Journal of Natural Products p. 1531 - 1534 (2011)
Update date:2022-07-29
Topics:
Silva, Luciano L.
Joussef, Antonio C.
The total synthesis of ( - )-julocrotine (1) starting from l-glutamic acid in 41% overall yield is described. The methodology utilizes protection, deprotection, and regioselection (carbonyl differentiation via oxazolidinone) protocols, and glutarimide ring formation is the key step.
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