Helvetica Chimica Acta p. 1391 - 1409 (1990)
Update date:2022-07-31
Topics:
Wagner, Ernst
Xiang, Yi-Bin
Baumann, Karl
Gueck, Juergen
Eschennmoser, Albert
Racemic aziridine-2-carbonitrile (rac-1) in MeCN solution reacts regioselectively (>90percent) with 2 equiv. of TsOH at room temperature to form the hydrotosylate of racemic O3-tosylserinenitrile (rac-2) via a β-ring opening (Scheme 2).A similar regioselective reaction takes place between rac-1 and H3PO4 to produce racemic O3-phosphoserinenitrile (rac-3) which is in turn a source of glycolaldehyde phosphate (=formylmethyl dihydrogenphosphate) under the conditions of a 'retro-Strecker' reaction in aqueous solution (Scheme 6).These experiments document a close structural relationship between the simplest of the sugar phosphates and an α-aminonitrile precursor.
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Doi:10.1016/j.bmc.2011.04.028
(2011)Doi:10.1039/c39900001154
(1990)Doi:10.1039/c39900001178
(1990)Doi:10.1246/cl.2011.300
(2011)Doi:10.1016/j.ica.2010.11.022
(2011)Doi:10.1016/j.jorganchem.2010.12.023
(2011)