10.1002/anie.201801305
Angewandte Chemie International Edition
COMMUNICATION
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9333–9403.
In summary, we have developed a photo-induced alkylation
reaction of pyridine N-oxides by using alkenes as alkylating
reagents. This strategy was successfully applied to the reaction
of a variety of N-oxides and alkenes, yielding pyridines having
benzylic and secondary alkyl groups at the ortho-position.
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Acknowledgements
This work was supported in part by Grants-in-Aid for Scientific
Research (S) (JP15H05756) and (C) (JP16K05694) from MEXT
and JST ACT-C Grant Number JPMJCR12Z9, Japan. W.Z.
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researchers.
a JSPS postdoctoral fellowship for foreign
Keywords: alkene • C–C bond cleavage • photocatalysis •
pyridine N-oxide • ortho-alkylation
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