Journal of Organic Chemistry p. 4473 - 4481 (1991)
Update date:2022-08-03
Topics:
Kanemasa, Shuji
Hayashi, Takeshi
Tanaka, Junji
Yamamoto, Hidetoshi
Sakurai, Tosio
The 1,3-dipolar cycloaddition of N-metalated ylides to chiral (E)-3-(1,3-disubstituted 4,5-diphenylimidazolidin-2-yl)propenoates proceeded highly diastereoselectively.The previously unknown absolute configuration of optically pure 1,2-dianilino-1,2-diphenylethane was determined from the absolute configuration of the cycloadducts.What diastereotopic olefin face of the α,β-unsaturated ester was attacked by the ylide was found to depend dramatically upon the nature of N substituents of the chiral controller as well as upon the bulkiness of the ester moiety of the ylide.
View MoreContact:+86-570-4336358
Address:No.87 Building,Tianqian,Sidu Town
Shaanxi King Stone Enterprise Company Limited
Contact:86-29-88353805,13609285751
Address:.209 Keji Road Hi-Tech industrial Develpment Zone .Xian China
ZHANGJIAGANG FREE TRADE ZONE YONG HAN INTERNATIONAL TRADING CO., LTD
Contact:86 512 57910558
Address:qianjin M road
HAINAN JINYING IMPORT AND EXPORT CO. LTD
Contact:+86-898-32875423
Address:A SECTION 19TH FL, TIMES SQUARE, NO.2 GUO MAO AVENUE HAIKOU, HAINAN, P. R. OF CHINA
Chengda Pharmaceuticals Co., Ltd.
Contact:+86-573-84601188
Address:hengshan Road 5# in Jiashan, zhejiang
Doi:10.1021/ja2084509
(2012)Doi:10.1246/cl.2011.1149
(2011)Doi:10.1021/ml200263y
(2012)Doi:10.1002/ardp.201000263
(2011)Doi:10.1002/anie.201103145
(2011)Doi:10.1002/ejoc.201801804
(2019)