ONE-POT SYNTHESIS OF 2-ARYLTHIAZOLINES
407
2H, CH2S); 13C NMR: δ 166.1, 150.1, 138.2, 135.9, 130.2, 125.9, 123.1, 63.2, 33.8; Anal.
calcd. for C9H8N2O2S: C 51.91, H 3.87, N 13.45, S 15.40; found: C 51.85, H 3.90, N
13.50, S 15.34.
1
2-(3-Fluorophenyl)thiazoline (3h). IR (KBr) ν: 1600 (CN); H NMR: δ 7.68–7.50
(m, 2H, Ar), 7.38 (d, 1H, J = 7.6 Hz. Ar), 7.22 (t, 1H, J = 7.6 Hz, Ar), 4.20 (t, J = 8.0 Hz,
2H, CH2N), 3.32 (t, J = 8.0 Hz, 2H, CH2S); 13C NMR: δ 165.8,163.9, 138.3, 131.2, 125.2,
118.2, 113.9, 64.2, 33.9; Anal. calcd. for C9H8FNS: C 59.65, H 4.45, N 7.73, S 17.69;
found: C 60.01, H 4.39, N 7.70, S 17.55.
2-(2-Pyridyl)thiazoline (3i). IR (KBr) ν: 1578 (CN); 1H NMR: δ 8.56 (d, 1H, J = 8.4
Hz. ArH), 8.04 (d, 1H, J = 8.4 Hz, ArH), 7.69–7.30 (m, 2H, ArH), 4.46 (t, J = 8.8 Hz, 2H,
CH2N), 3.32 (t, J = 8.8 Hz, 2H, CH2S); 13C NMR: δ 166.9, 152.4, 152.0, 136.9, 132.6,
124.2, 63.6, 34.2; Anal. calcd for C8H8N2S: C 58.51, H 4.91, N 17.06, S 19.52; found: C
58.60, H 4.99, N 17.01, S 19.55.
2-(4-Pyridyl)thiazoline (3j). IR (KBr) ν: 1582 (CN); 1H NMR: δ 8.71 (dd, 2H, J =
1.6, 4.8 Hz. ArH), 7.72 (dd, 2H, J = 1.6, 4.8 Hz, ArH), 4.49 (t, J = 8.4 Hz, 2H, CH2N),
3.42 (t, J = 8.8 Hz, 2H, CH2S); 13C NMR: δ 167.2, 150.2, 144.3, 125.2, 62.8, 34.1; Anal.
calcd. for C8H8N2S: C 58.51, H 4.91, N 17.06, S 19.52; found: C 58.55, H 4.92, N 17.05,
S 19.58.
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