Journal of Medicinal Chemistry p. 249 - 255 (1993)
Update date:2022-08-02
Topics: Synthesis Evaluation Inhibitors Phenyl Pyridyl 2-pyridinone HIV-1 reverse transcriptase 3-aminopyridin-2(1H)-one
Wai
Williams
Bamberger
Fisher
Hoffman
Hudcosky
MacTough
Rooney
Saari
Thomas
Goldman
O'Brien
Emini
Nunberg
Quintero
Schleif
Anderson
In an ongoing effort to develop novel nonnucleoside, specific human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) inhibitors, a series of 3-[(pyridylmethyl)amino]- and 3-[(phenylmethyl)amino]-2- pyridinone derivatives was synthesized an
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