Research on Chemical Intermediates p. 3399 - 3405 (2013)
Update date:2022-08-04
Topics:
Pardeshi, Santosh P.
Patil, Sachin S.
Patil, Amar A.
Bobade, Vivek D.
An efficient synthesis of vinyl-substituted 1,3,4-oxadiazoles using o-nitrophenyl sulfoxide precursor via syn-elimination reaction using sodium acetate in THF is described. This method is cost effective as it uses cheap o-nitrothiophenol and can be used in the synthesis of vinyl intermediates during synthesis of bioactive compounds, which avoids the use of any toxic metals.
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