10.1002/ejoc.201901646
European Journal of Organic Chemistry
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Experimental Section
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General procedure for acetoxylation of 2-neopentyl-
sulfinylacetamides
A 4 mL vial was charged with the substrate (0.1 mmol, 1.0 equiv.),
Pd(OAc)2 (2.3 mg, 0.01 mmol, 10 mmol%), PhI(OAc)2 (99.6 mg,
0.3 mmol, 3.0 equiv) and AcOH (0.41 mL, 0.25 M). The mixture
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and the solvent was evaporated. The crude product was purified
on silica gel (petroleum ether/EtOAc or toluene/acetone).
General procedure for Pd-catalyzed alkenylation of 2-
neopentylsulfinylacetamides
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A 4 mL vial was charged with the cyclopropanol (0.1 mmol, 1.0
equiv.), Pd(OAc)2 (2.3 mg, 0.01 mmol, 10 mmol%), benzoquinone
(11.9 mg, 1.1 mmol, 1.1 equiv.) and toluene (1 mL, 0.1 M). The
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Acknowledgments
We are grateful for the financial support from the Belarusian
Foundation for Fundamental Research (project X17-073).
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Keywords: C-H acetoxylation • C-H alkenylation • arylacetic
acids • cyclopropanols • ring-opening
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