Tetrahedron Letters p. 3711 - 3714 (1992)
Update date:2022-08-04
Topics:
Salvati, Mark E.
Moran, Edmund J.
Armstrong, Robert W.
A simple and rapid method has been developed for the isolation of thermally labile DNA alkylation products. Use of calf thymus DNA in combination with size exclusion filtration provides good yields >40% of chlorambucil-guanine adducts. Application of this
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Doi:10.1016/0040-4039(92)88093-K
(1992)Doi:10.1002/anie.201204346
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(1991)Doi:10.1016/j.bmc.2013.03.072
(2013)