Journal of Organic Chemistry p. 7175 - 7187 (1992)
Update date:2022-07-30
Topics:
Shono, Tatsuya
Kise, Naoki
Fujimoto, Taku
Tominaga, Naoto
Morita, Hiroshi
Electroreduction of γ- and δ-cyano ketones in i-PrOH with Sn cathode gave α-hydroxy ketones and their dehydroxylated ketones as the intramolecularly coupled products.Guaiazulene, (-)-valeranone, polyquinanes, dihydrojasmone, methyl dihydrojasmonate, and rosaprostol have been synthesized by utilizing this electroreductive intramolecular coupling of γ- and δ-cyano ketones in one of the key steps.Similarly, electroreduction of a mixture of ketone and nitrile gave the corresponding intermolecularly coupled product.The product obtained by the electroreductive intermolecular coupling of (+)-dihydrocarvone with acetonitrile has been found to be the precursor of an effective chiral ligand for the enantioselective addition of diethylzinc to aldehydes.
View MoreAnhui Biochem United Pharmaceutical Co., Ltd.
Contact:0086 551 5167062 / 5228268
Address:No. 30 Hongfeng Road, Hi-Tech Development Zone, Hefei (230088), China
Contact:+86-574-87065746
Address:10th Floor, No.787 Baizhang East Road,
Contact:+86-25-83719363
Address:106-7 Chunnan Rd, Chunxi Town, Gaochun, Nanjing, China
Anhui Eapearl Chemical Co., Ltd.
Contact:86-562-5858458
Address:358 South Huaihe Road
Jinan Chenghuishuangda Chemical CO.,Ltd
website:http://www.jnchsd.com
Contact:+86-531-58897082
Address:No.2350, Kaituo Road, High-tech Development District, Jinan City, Shandong, China
Doi:10.1002/ejoc.201201111
(2012)Doi:10.1080/00397919208019090
(1992)Doi:10.1021/om5002606
(2014)Doi:10.1021/jm00103a003
(1992)Doi:10.1039/c2sc21754f
(2013)Doi:10.1002/aoc.4001
(2018)