Tetrahedron p. 6821 - 6826 (1992)
Update date:2022-08-04
Topics:
Gonsalves, Antonio M. d'A. Rocha
Melo, Teresa M. V. D. Pinho e
Benzyne has been generated from benzenediazonium-2-carboxylate in the presence of several 1,2,4-triazines 1 and isoquinolines 2 have been isolated in moderate yield. 1-Aminobenzotriazole was also used as the source of benzyne and isoquinolines were again isolated in moderate yield from these reactions. 4-Methylbenzyne, which was generated from 5-methylanthranilic acid, reacted unselectively with the triazines to give mixtures of 6- and 7-methylisoquinolines 3 and 4.On the other hand reactions of 3-methylbenzyne with the triazines 1d and 1e proceeded with high regioselectivity, giving only the 5-methylisoquinoline 5a and the 8-methylisoquinoline 6b, respectively.
View MoreShanghai Yuantai Chemical Products Co., Ltd
Contact:021--66129803
Address:Chengyin Road,Shanghai,China
Zhejiang kehong chemical co., ltd
Contact:0086-575-85522000
Address:xiner center RD binhai industrial zone shaoxing zhejiang province P.R.China,312073
Luzhou North Chemical Co., Ltd.
Contact:+86-830-2796784;+86-830-2796776
Address:Gaoba, Longmatan District, Luzhou, Sichuan Province
HAINAN JINYING IMPORT AND EXPORT CO. LTD
Contact:+86-898-32875423
Address:A SECTION 19TH FL, TIMES SQUARE, NO.2 GUO MAO AVENUE HAIKOU, HAINAN, P. R. OF CHINA
Zhonghao (dalian) Research and Design Institute of Chemical Industry Co., Ltd
Contact:+86 411 84674606
Address:201, Huangpu Road , Shahekou District, Dalian ,116023-China
Doi:10.1021/jo00104a019
(1994)Doi:10.1016/j.tetlet.2013.04.130
(2013)Doi:10.1039/c3cc43199a
(2013)Doi:10.1246/cl.1992.1677
(1992)Doi:10.1016/0957-4166(95)00303-7
(1995)Doi:10.1016/j.ejmech.2013.03.046
(2013)