European Journal of Medicinal Chemistry p. 495 - 502 (1992)
Update date:2022-08-03
Topics:
Massa
Di Santo
Retico
Artico
Simonetti
Fabrizi
Lamba
The synthesis of some 2-aryl-1-(4-methoxyphenyl)-1-(1H-imidazol-1-yl)ethane derivatives and related 1H-1,2,4- and 1H-1,3,4-triazoles is described. The molecular structure of new derivatives has been established by 1H NMR spectra and X-ray crystallographic analysis. When tested in solid agar cultures the azole derivatives showed from moderate to potent in vitro antifungal activity against Candida albicans and Candida spp.
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