Journal of medicinal chemistry p. 3120 - 3128 (1993)
Update date:2022-07-30
Topics:
Humber
Bamford
Bethell
Cammack
Cobley
Evans
Gray
Hann
Orr
Saunders
et al.
The C2-symmetric diester 1 was identified by random screening as a novel inhibitor of HIV-1 proteinase. This led to the preparation of a series of related more potent amides from readily accessible penicillins. Many of the compounds showed potent antivira
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