Journal of Organic Chemistry p. 4837 - 4843 (1993)
Update date:2022-07-30
Topics:
Ma, Zhenkun
Huang, Qingtao
Bobbitt, James M.
A new synthesis of unsymmetrical 2,2,6,6-tetraalkyl-4-piperidones from acetonin (2,2,4,4,6-pentamethyl-2,3,4,5-tetrahydropyrimidine) and several ketones is described.When the ketone was a naturally occurring optically active ketone, the piperidones were optically active.The piperidones were converted to unsymmetrical TEMPO-type nitroxides and chiral nitroxides.The optically active nitroxides were used as catalysts for oxidations or converted to chiral oxoammonium salts.The structures of the chiral compounds were determined by 2D (1)H and (13)C NMR, and the cyclic voltammetric properties of the various nitroxides were measured.Several other pyrrolidine oxoammonium salts were prepared, and both types were used as oxidizing agents.Preliminary results of chiral oxidations are presented.
View MoreHebei Fulong Import & Export Co., Ltd.
Contact:86-311-87795661
Address:15A19 Zhongyuan Building,368 Youyi North Street,Shijiazhuang 050070,China
Lianyungang Ningkang Chemical Co., Ltd
Contact:.+86-518-88588008
Address:http://www.chemnk.com
TIANJIN ZHONGXIN CHEMTECH CO.,LTD.
Contact:86-022-89880739
Address:10B, Pan China International Center, No. 931 YingKou Road, TangGu, Tianjin, China, 300451
Contact:+86-717-6370352
Address:168 Chengdong Avenue, Yichang, Hubei 443003, P. R.China
Zhejiang PRIMAR Import & Export Trade Co., Ltd.
Contact:86-570-3630818
Address:No.1Puzhuyuan,Quhua,Zhejiang Province,China324004
Doi:10.1021/ja411737c
(2014)Doi:10.1002/ejic.201900537
(2019)Doi:10.1021/acs.joc.6b01683
(2016)Doi:10.1021/jo01266a033
(1968)Doi:10.1016/S0022-1139(00)80391-7
(1993)Doi:10.1021/ja01148a074
(1951)