Journal of the Chemical Society. Chemical communications p. 465 - 467 (1986)
Update date:2022-07-29
Topics:
Stark, W. Marshall
Hart, Graham J.
Battersby, Alan R.
A macrocyclic spiro-lactam is synthesised which closely resembles the spiro system proposed as a biosynthetic intermediate for uro'gen-III; this spiro-lactam powerfully inhibits cosynthetase, the enzyme responsible for forming uro'gen-III.
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