Journal of Antibiotics p. 1812 - 1818 (1993)
Update date:2022-07-30
Topics:
Naruse
Oka
Konishi
Oki
The structures of antiviral antibiotics kistamicins A and B have been determined by a combination of chemical degradation and spectral analysis. They are commonly composed of D-tyrosine 3,5-dihydrophenylglycine a biphenyl ether bis-amino acid and a diphenyl substituted indole tris-amino acid forming a tricyclic ring structure. Kistamicin B possessed a phenethylamide at the amino terminal of kistamicin A. They are structurally related to the nuclei of the vancomycin group antibiotics particularly to antibiotic complestatin.
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