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Dalton Transactions
Page 4 of 4
ARTICLE
Dalton Transactions
toluene, aromatic amine (1 mmol) and aromatic bromide (1
mmol) was added and the reaction mixture was subjected for
conventional heating (110oC for 5 d) as well as microwave
heating (184oC for 15-30 min). Reaction completion monitored
by TLC and NMR, and the compound was extracted in diethyl
ether and organic layer was washed with distilled water.
Further isolation and purification was done by using column
chromatography in n-Hexane (100%).
Microwave method: Required amount of NaOtBu (7 eq), 5
mol% of Pd (dba)2 and 5 mol% PNP ligand (1 or 2) was taken
in microwave tube inside the glove box. 4 mL of toluene added
to that tube and required amount of aromatic amine and
aromatic bromide was added and subjected to microwave
heating (184oC for 15-30 min) reaction. Reaction completion
monitored by TLC and NMR and some of the compounds
purified using column chromatography using ethyl acetate and
n-Hexane mixture (2% EA + 98% n-Hexane).
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Crystallographic details
Crystallography Reflections were collected on a Bruker Smart
Apex Duo diffractometer at 100 K using Mo Kα radiation (λ =
0.710ꢀ73 Å) for 3d, 3h, and 3i. The structures were solved by
direct methods and refined by full-matrix least-squares
methods against F2 (SHELXL-2014/6). Crystallographic data
(including structure factors) for the structures reported in this
paper have been deposited with the Cambridge
Crystallographic Data Centre with no. 1872189-1872191. The
copies of the data can be obtained free of charge on
application to the CCDC, 12 Union Road, Cambridge CB2 1EZ,
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Conflicts of interest
There are no conflicts to declare.
Notes and references
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