Nucleosides and Nucleotides p. 1977 - 1989 (1994)
Update date:2022-09-26
Topics: Characterization Arylation Deprotection Purification Starting Material Biological Assays Structure-Activity Relationship (SAR) Studies Protection of Reactive Groups Iodination Azidation
Shoshani
Qiu
Johnson
Johnson
Potential affinity probes for adenylyl cyclase were synthesized that take advantage of the enzyme's sensitivity to 'P'-site-mediated inhibition by 2',5'-dideoxyadenosine analogs and its tolerance for large 3'-ribose substitutions. We report the synthesis
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