Hydrogen-Bond Interactions ofNicotine and Acetylcholine Salts
FULL PAPER
The decrease in the OH absorption ofthe donor induced by the introduc-
tion ofthe salt into solution is a consequence ofthe association ofpFP
with all the available accepting sites. Therefore, the calculated equilibri-
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um constant Kt is the sum ofthe individual 1:1 equilibrium constants
for the C+ cation and Picꢀ anion [Equations (12)–(14)].
4-FC6H4OH þ CþPicꢀ Ð 4-FC6H4OH Á Á Á CþPicꢀ
4-FC6H4OH þ CþPicꢀ Ð 4-FC6H4OH Á Á Á PicꢀCþ
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ð12Þ
ð13Þ
KPicꢀ
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¼ KCþ þ KPicꢀ
ð14Þ
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Acknowledgements
The authors gratefully acknowledge AurØlien Planchat for his active par-
ticipation in the experimental work, Prof. Anthony J. Stone for providing
the Orient program and the Centre de Calcul Intensifdes Pays de la
Loire (CCIPL), the Centre Informatique National de lꢀEnseignement Su-
pØrieur (CINES) and the Institut Des Ressources en Informatique Scien-
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