Organic Letters
Letter
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smelling byproducts, and employ commercial nucleophilic
reagents. These practical qualities should appeal to industrial-
scale preparation of pharmaceutically relevant perfluoroalkyl
sulfides.
ASSOCIATED CONTENT
* Supporting Information
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sı
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The Supporting Information is available free of charge at
Experimental procedures and characterization data for
AUTHOR INFORMATION
Corresponding Author
■
Gavin Chit Tsui − Department of Chemistry, The Chinese
University of Hong Kong, Shatin, New Territories, Hong Kong
Authors
Ziwei Luo − Department of Chemistry, The Chinese University
of Hong Kong, Shatin, New Territories, Hong Kong SAR
Xinkan Yang − Department of Chemistry, The Chinese
University of Hong Kong, Shatin, New Territories, Hong Kong
SAR
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Lu, L.; Shen, Q. Org. Lett. 2019, 21, 6347−6351. (b) Li, H.; Cheng,
Z.; Tung, C.-H.; Xu, Z. ACS Catal. 2018, 8, 8237−8243. (c) Liu, X.;
Liang, Y.; Ji, J.; Luo, J.; Zhao, X. J. Am. Chem. Soc. 2018, 140, 4782−
4786. (d) Luo, J.; Cao, Q.; Cao, X.; Zhao, X. Nat. Commun. 2018, 9,
527−535. (e) Li, H.; Shan, C.; Tung, C.-H.; Xu, Z. Chem. Sci. 2017, 8,
2610−2615. (f) Wang, Q.; Qi, Z.; Xie, F.; Li, X. Adv. Synth. Catal.
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Complete contact information is available at:
Notes
The authors declare no competing financial interest.
ACKNOWLEDGMENTS
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This work was supported by the Research Grants Council of
Hong Kong (CUHK 24301217) and the Chinese University of
Hong Kong (the Faculty Strategic Fund for Research from the
Faculty of Science and the Direct Grant for Research). We also
thank the Key Laboratory of Organofluorine Chemistry,
Shanghai Institute of Organic Chemistry, Chinese Academy
of Sciences, for funding.
́
Langlois, B. R.; Bacque, E. Angew. Chem., Int. Ed. 2009, 48, 8551−
8555.
(11) Nucleophilic CF3 sources are usually much less expensive than
electrophilic ones. For a price comparison, see: Natte, K.; Jagadeesh,
R. V.; He, L.; Rabeah, J.; Chen, J.; Taeschler, C.; Ellinger, S.;
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