Tetrahedron p. 971 - 986 (1996)
Update date:2022-08-05
Topics:
Urban
Knuhl
Helmchen
Asymmetric shielded 2-oxo-cyclopentenecarboxylates 6n and 6x were prepared by transesterification of 2-oxo-cyclopentanecarboxylate 2 with camphor derived concave alcohols 1n and 1x and by subsequent introduction of a double bond via phenylselenides. Diastereoselective conjugate addition of equimolar amounts of mixed cuprates at -78°C and deprotection by ethanolysis gave enantiomerically pure 5-substituted 2-oxo-cyclopentanecarboxylates 13-18 and ent-13-18, valuable as chiral building blocks in natural product synthesis.
View MoreXinjiang Zhongtai Chemical Co., Ltd.
Contact:+86-991-8788172
Address:NO.78 XISHAN RD.URUMQI,CHINA
Jiande City Silibase Silicone New Material Manufacture Co., Ltd.
Contact:15967177856
Address:Genglou Industrial Development Area
Guangxi Nanning Guangtai Agriculture Chemical Co.,Ltd
Contact:+86-771-2311266
Address:Room703,Building12, Software Park Phase II,NO.68,Keyuan Road,Nanning City,Guangxi,China
Shanghai AoBo Bio-Pharmaceutical Technology Co., Ltd.
Contact:+86-21-51320130-801, 816
Address:Room 601, No. 1011, Halei Road, Zhangjiang High-Tech Park, Pudong, Shanghai
Jiangxi Huashi Pharmaceutical Co., Ltd
Contact:+86-795-4509628
Address:Ningbo Ave., Fengtian Industrial Park, Fengxin Country, Jiangxi, China.
Doi:10.1016/0040-4039(95)01734-Y
(1995)Doi:10.1021/jm950514m
(1996)Doi:10.1016/j.bmcl.2020.127443
(2020)Doi:10.1002/chem.202101080
(2021)Doi:10.1016/S0040-4039(01)01106-6
(2001)Doi:10.1021/jm00070a008
(1993)