European Journal of Medicinal Chemistry p. 769 - 778 (1995)
Update date:2022-08-03
Topics:
Yebga, A.
Menager, S.
Verite, P.
Farnoux, C. Combet
Lafont, O.
In order to study the competition between hepatic hydroxylation and desulfuration in the thiobarbiturate series, two compounds bearing a branched side chain with a tertiary carbon atom in position ω-1 were administered to rats over about one week.Urine and faeces were collected and extracted.The metabolites isolated were identified.It was shown that desulfuration was not the major metabolic pathway, and that, when it took place, it remained a minor process and was accompanied by γ-hydroxylation into a tertiary alcohol. thiobarbiturate series / metabolism / oxidation / desulfuration
View MoreZIBO ZEYUAN IMPORT & EXPORT CO.,LTD
Contact:+86-533-6723789
Address:Zhangdian District Youth League West Blue Diamond International 408 121
Nanjing Samwon International Limited
Contact:+86-25-84873444
Address:1108, BLDG B, New Century Plaza, No 1, South Taiping Rd.,
Contact:13357117572
Address:No.149 Shiji dadao Road.
Contact:0519-85170101-802
Address:Fifth Floor,B of Beihua Buliding,520 Road of Science and Education City,Changwu middle road NO.801,Wujin District,Changzhou,Jiangsu province
Chiral Quest (Suzhou) Company Ltd
website:http://www.chiralquest.com
Contact:+86-0512-62956066
Address:B1/9, 218 Xinghu Street, Suzhou Industrial Park
Doi:10.1016/0008-6215(95)00199-4
(1995)Doi:10.1246/bcsj.40.2950
(1967)Doi:10.1134/S1070428014020237
(2014)Doi:10.1016/S0040-4039(00)73257-6
(1994)Doi:10.1016/S0040-4039(00)76974-7
(1994)Doi:10.1071/CH15065
(2015)