Monatshefte fur Chemie p. 1367 - 1374 (1995)
Update date:2022-08-03
Topics:
Weis, R.
Vora, U. di
Seebacher, W.
Schweiger, K.
6-Phenylimino-3,6-dihydro-2H-thiopyran-4-amines (1) were converted to 1-phenyl-5,6-dihydropyridine-2(1H)-thiones (3).Those were alkylated and hydrolyzed, thus yielding 6-methylthio-1-phenyl-2,3-dihydro-4(1H)-pyridinones (5).Finally, the methylthio group was removed with Raney nickel giving the title compounds 6.The relative configurations of the formed diastereomeric dihydropyridinones have been investigated by NOE measurements. - Keywords: Dihydropyridine-2(1H)-thiones; Dihydrothiopyran-4-amines; 1-Phenyl-2,3-dihydro-4(1H)-pyridinones; Tetrahydropyridiniumiodides
View Morepuyang hongda shengdao new material co.,ltd.
Contact:+86-393- 4896278
Address:No.29 East Zhongyuan Road
Improve Medical Technology(Nanxiong) Co., Ltd
Contact:86-751-3836997
Address:No.33, Pingan First Road, Fine Chemical Industry Base, Nanxiong City, Shaoguan, Guangdong, China
SHANDONG ZHANHUA YONGHAO PHARMACEUTICAL TECH.CO.,LTD
Contact:+86-576-88685096
Address:GENGJU VILLAGE NORTH ONE KILOMETER,ZHANHUA DISTRICT,BINZHOU CITY,SHANDONG PROVINCE,CHINA.
NINGBO PANGS CHEM INT’L CO.,LTD.
Contact:+86-574-27666845
Address:FLOOR 21,BUILDING NO.11,XIN TIAN DI,NO.689 SHI JI ROAD,NINGBO CHINA
Shandong united-rising pharmaceutical cooperation.,ltd.
Contact:008653187965009
Address:171No., Jing5 Road, Shizhong District, Jinan, China
Doi:10.1021/jo9520856
(1996)Doi:10.1248/cpb.46.1522
(1998)Doi:10.1021/ja01493a012
(1960)Doi:10.1021/ol036121w
(2004)Doi:10.1246/cl.1996.99
(1996)Doi:10.1021/jo951897z
(1996)