Journal of Fluorine Chemistry p. 91 - 93 (1996)
Update date:2022-07-31
Topics:
Nemeth, Gabor
Rakoczy, Eva
Simig, Gyula
α-(Trifluoromethyl)phenylacetic acid (1) was synthesized in good overall yield starting from the cyanohydrin of α,α,α-trifluoroacetophenone, via hydrogenolysis of α-mesyloxy-α-(trifluoromethyl)phenylacetamide or ethyl α-mesyloxy-a-(trifluoromethyl)phenylacetate followed by acidic hydrolysis.
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(1996)Doi:10.1021/jo960125f
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(1996)